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The journal publishes timely critical reviews of topics related to medicinal research broadly defined to which the authors have made significant contributions. Appropriate topics include but are not limited to the underlying pathophysiology of important diseases and disease vectors; therapeutic approaches to the treatment of various diseases; the properties of molecular targets for therapeutic agents; important new methodologies facilitating the search for therapies; genomics and proteomics; structure-activity correlations of drug series; the development of new imaging and diagnostic tools; drug metabolism; drug delivery; chemical pharmacological pharmacokinetic pharmacodynamic and clinical characteristics of importance. Reviews are mainly solicited by the editors; however voluntary contributions are also encouraged. In the latter case potential authors are asked to contact either co-editor with an outline before beginning to write in order to avoid duplication of effort and to ensure suitability of the topic and its level of coverage.
该杂志及时发表与医学研究相关的评论，广泛定义了作者已作出重大贡献的主题。适当的主题包括但不限于重要疾病和疾病载体的潜在病理生理学;各种疾病的治疗方法;目的研究药物分子靶点的性质。促进寻找治疗方法的重要新方法;基因组学和蛋白质组学;药物系列的构效关系开发新的成像和诊断工具;药物代谢;药物输送;化学药物的药代动力学、药效学和临床特点的重要性。评论主要由编辑征求意见;不过，也鼓励自愿捐款。在后一种情况下，潜在的作者被要求在开始写作前与合作编辑中的任何一位联系提纲，以避免重复工作，并确保主题及其报道水平的适宜性。
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