期刊简介
Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry.We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products.Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal.More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.Organic synthesis: We welcome important research in all areas of organic synthesis, including studies on small organic molecules and biomolecules, and studies that report purely synthetic work without biological data. Total or multistep syntheses should report new or improved strategies or methods, or a more efficient route to the target compound. Methodology studies should show a significant improvement on known methods. Research that extends known methodology to a different class of compounds is generally not suitable, unless that class is significantly different in scope to previously reported methodology.Physical and theoretical organic chemistry: We welcome studies that report new models of reactivity, selectivity, bonding or structure, or new computational methods and have relevance for the design of subsequent experiments. That relevance should be clearly justified in the paper. Relevance is perhaps most clearly demonstrated by the description of testable predictions derived from the results of the reported theoretical work; the tests of these predictions could be contained in the same paper in which the predictions are described. Computational research that merely reproduces experimental data is not suitable for OBC.Chemical biology: We welcome articles that report new or improved methodologies in the chemical aspects of chemical biology, including design, development and use of chemical tools, chemical studies of biomolecules such as carbohydrates, proteins and nucleic acids or biological processes such as protein-protein interactions and epigenetics, and chemical methods such as imaging and labelling techniques.Supramolecular, macromolecular and organic materials: We welcome studies that report important new work in the molecular design of supramolecular or macromolecular compounds or organic materials either with a strong component in organic synthesis or with novel organic structural features. You may wish to consider our materials journals for articles outside this scope.Sensors: We publish articles describing sensors for ions and/or molecules provided that: (a) they address targets and situations of practical relevance; and (b) they represent significant and demonstrable improvements on previous methodology. In particular, sensors for species in artificial surroundings (for example, hydrophilic ions in organic solvents) will not typically be acceptable for publication.Medicinal chemistry: We welcome studies that report significant synthetic or bioorganic research that is directed towards medicinal chemistry applications. Studies that show routine syntheses accompanied by biological testing are generally not suitable for OBC. Our sister journal, MedChemComm, is more suitable for articles that report significant research in core medicinal chemistry disciplines.Natural products: We welcome articles that report new and interesting syntheses of natural products (see Organic Synthesis guidelines above) or chemical studies of biosynthetic pathways. Isolation or identification studies are welcome when the compound being reported:1) Has a novel structural class with unreported carbon skeleton, unusual functional groups or unusual modifications and/or2) Displays a potent or unexpected biological activity or an unexpected mechanism of action. Routine isolation studies are not suitable for OBC.
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